Cardinals vs. Reds Predictions & Picks: Odds, Moneyline, Spread - May 25

Thursday's contest features the St. Louis Cardinals (22-29) and the Cincinnati Reds (21-28) squaring off at Great American Ball Park in what should be a competitive matchup, with a projected 6-4 win for the Cardinals according to our computer prediction. First pitch is at 12:35 PM ET on May 25.

The probable pitchers are Miles Mikolas (2-1) for the Cardinals and Luke Weaver (1-2) for the Reds.

Cardinals vs. Reds Game Info & Odds

• When: Thursday, May 25, 2023 at 12:35 PM ET
• Where: Great American Ball Park in Cincinnati, Ohio
• How to Watch on TV: MLB Network
• Live Stream: Watch this game on Fubo!

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Cardinals vs. Reds Score Prediction

Our pick for this contest is Cardinals 6, Reds 5.

Total Prediction for Cardinals vs. Reds

• Total Prediction: Over 9.5 runs

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Read More About This Game

Cardinals Performance Insights

• In six games as the favorite over the last 10 matchups, the Cardinals have a record of 3-3.
• In its last 10 games with a total, St. Louis and its opponents have failed to hit the over three times.
• There has not been a spread set for any of the Cardinals' last 10 games.
• The Cardinals have entered the game as favorites 27 times this season and won 12, or 44.4%, of those games.
• St. Louis is 9-14 this season when entering a game favored by -125 or more on the moneyline.
• The moneyline for this contest implies a 55.6% chance of a victory for the Cardinals.
• St. Louis has scored 261 runs this season, which ranks fifth in MLB.
• The Cardinals have a 4.41 team ERA that ranks 19th among all MLB pitching staffs.

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Cardinals Schedule